The Official Blog of the Counsel TxP Software Package. Wednesday, May 12, 2010. What is a Psychoactive Drug? A psychoactive drug is any chemical substance that acts primarily upon the central nervous system to alter perception, mood, consciousness, or behavior. Only those drug classes that are used by medical doctors at the prescription level will be discussed in this fact sheet. Many illegal street drugs are also psychoactive. Warning for food and drugs lethality.

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